Finally got around to watching the episode (being on the road for two weeks sucks). I too have some issues with Bono's comments on circumcision. I'm personally opposed to it, especially on infants who can't freely choose the procedure. As pointed out, the studies are inconsistent. I can get behind suggesting it for third world African countries as studies have shown it reduces the risk of transmission for them, but in industrialized wealthy nations I don't think it's necessary. It remains in my mind a barbaric, unnecessary procedure most of the time.